Patients with mild cognitive impairment Spatial cognition Episodic memory Prefrontal cortex Virtual reality Hippocampus
Conditions
Interventions
This program was programmed in the Unity game engine and ran using the laptop computer. Participants used a joystick to freely move their viewpoint (forward,
turn left,
or turn right) in the virtual reality environment. All participants in the EG were given an opportunity to underwent two sessions in an empty environment,
allowing the participants to familiarize themselves with the environment and the control of the joystick until the participants felt familiar with them enough. Subsequently,
the participants performed training sessions. During the training sessions,
the participants were immersed in one environment with boundary cues consisted rocks and ocean. No landmarks were presented during the training sessions,
excluding compensatory navigation strategies. Participants’ location was randomized in the environment and they were instructed to look around. There was a gem in the environment and the participant
another gem was presented again in a different location from the previous gem and they were instructed to move the new gem in the same way as before. Only one gem was presented at a time,
each gem would disappear after the participants reached it and the next gem in sequence would appear. After reaching second gem,
a visual instruction on the virtual scene asking the participants to walk back to their starting location was projected. When they estimated their starting location. They pressed a confirmation button
a feedback was provided “good job†whereas i
Experimental Behavioral,Active Comparator Behavioral
Spatial cognitive training based on virtual realtiy ,Computerized sptial cognitive training
Sponsors
There is no sponsor
There is no sponsor
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: (a) subjective memory complaint (b) objective memory impairment defined by score on the Seoul Neuropsychological Screening Battery (c) intact general cognitive function as determined by score on the Korean version of the Mini-Mental State Examination (MMSE-K) (d) intact activities of daily living as determined by score on the Seoul instrumental activities of daily living score
Exclusion criteria
Exclusion criteria: (a) dementia diagnosed by physicians (b) presence of neurological or psychiatric disorders (c) moderate or severe depressive symptom as determined by score on the Korean version of the Geriatric Depression Scale (d) presence of auditory or visual impairments (e) participation in any programs to improve cognitive function within one month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spatial cognition Before and after the 8-week intervention the Weschsler Adult Intelligence Scale-Revised Block Design test,Episodic memory Before and after the 8-week intervention The Seoul Verbal Learning Test | — |
Secondary
| Measure | Time frame |
|---|---|
| Acitivy in prefrontal cortex Before and after the 8-week intervention Changes in oxygenated hemoglobin | — |
Countries
Republic of Korea
Contacts
Public ContactJin-Hyuck Park
Soonchunhyang University, Dept. of Occupational Therapy
Outcome results
None listed