OA Knee going on total knee arthroplasty -
Conditions
Interventions
Single-
shot anterior femoral cutaneous nerve block and adductor canal block with iPACK block is perform by 0.25% Chirocaine 60 ml,
epinephrine 0.3 mg and ketorolac 30 mg
The sham of local infiltration analgesia is done by NSS intra-
operatively.
Continuous adductor canal block under ultrasound guidance is performed by injecting 0.25% levobupivacaine 20 ml and followed by 0.15% levobupivacaine 5 ml/hr for 60 hours ,Single-
shot sham anterior femoral cutaneous nerve block and adductor canal block with iPACK block under ultrasound-
guided is performed by injecting of 0.9% NSS 5 ml each blocks.
Local infiltration analgesia is performed intra-
operatively. The cocktail consists of Levopupivacaine 150 mg,
and Adrenaline 0.3 mg combined with NSS 60 ml.
Continuous adductor canal block under ultrasound guidance is performed by injecting 0.25% levobupivacaine 20 ml and followed by 0.15% levobupivacaine 5 m
Experimental Procedure/Surgery,Experimental Procedure/Surgery
Anterior femoral cutaneous nerve block and adductor canal block with iPACK block,Local infiltration analgesia
Sponsors
none
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patient who was scheduled for total knee arthroplasty at King Chulalongkorn Memorial Hospital ASA class 1 to 3 ASA class 1 A normal healthy patient ASA class 2 A patient with mild systemic disease Mild diseases only without substantive functional limitations ASA class 3 A patient with severe systemic disease but not threaten to life Body mass index BMI between 18 to 40 kg m2
Exclusion criteria
Exclusion criteria: refuse to participate this study unable to cooperate or cognitive impairment eg dementia allergy to any drug in this study contraindication to neuraxial anesthesia eg coagulopathy contraindication to NSAIDs Ketorolac and Celebrex in this study chronic opioids use or diagnosed of neuropathic pain unable to performed Time up and go test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain score 24 hours Numerical pain rating scale | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative pain score of anterior knee pain at rest 6, 24, 48 hours and 3, 5 days and 1, 2 weeks and 1, 2, 3 months Numerical pain rating scale,postoperative pain score of anterior knee pain on movement 6, 24, 48 hours and 3, 5 days and 1, 2 weeks and 1, 2, 3 months Numerical pain rating scale,postoperative pain score of posterior knee pain at rest 6, 24, 48 hours and 3, 5 days and 1, 2 weeks and 1, 2, 3 months Numerical pain rating scale ,postoperative pain score of posterior knee pain on movement 6, 24, 48 hours and 3, 5 days and 1, 2 weeks and 1, 2, 3 months Numerical pain rating scale,postoperative opioids consumption 12, 24, 48 hours Milligram of Morphine Consumption,Degree of knee flexion and extension Postoperative 0, 1, 2 Days Degree of range of motion,Timed up and go test Postoperative 1, 2 days Rehabilitation after surgery,Postoperative Complication Postoperative 0, 1, 2 Days Postoperative Nausea Vomiting, Dizziness, Fall, Sleep disturbance,Length of stay Postoperative to discharge out of hospital hours,Patient satisfaction Postoperative day 2 Satisfactory score (1-10) | — |
Countries
Thailand
Contacts
Public ContactWirinaree Kampitak
unaffiliated
Outcome results
None listed