Single edentulous tooth patient who requires implant placement in esthetic zone -
Conditions
Interventions
Xenograft ,Xenograft with Acemannan 50 mg.
Placebo Comparator Biological/Vaccine,Experimental Biological/Vaccine
Xenograft,Xenograft with Acemannan
Sponsors
Graduate school, Chulalongkorn University
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patient who has single edentulous area and can achieve appropriate 3 dimensional positions of implant placement in esthetic zone. 2. Patient with age ≥ 20 years old. 3. Patient who has mild to moderate atrophy of bone. ( loss of 25-50% bone width and bone height from radiograph ) 4. Patient with sufficient keratinized gingiva. 5. Patient who are healthy or well-controlled systemic disease.
Exclusion criteria
Exclusion criteria: 1. Patient who had previously received bone graft on the site to be operated. 2. Smokers. 3. Patient with poor plaque control and untreated chronic periodontitis. 4. Patient with acute infection such as severe swelling, suppuration and abscess. 5. Patient who is pregnant or lactating. 6. Patient who has previously received radiation therapy in head and neck regions. 7. Patient who has received chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bone formation mmediate post-operative, post-operative 3 months, and post-operative 6 months measure in clinic and radiograph | — |
Secondary
| Measure | Time frame |
|---|---|
| Size of outbreaks of HFMD in childcare centers/kindergartens in treatment versus control arms. 1 year Incidence of outbreak,Association of low serum vitamin A level and severity of HFMD in both arms 1 year Odds ratio | — |
Countries
Thailand
Contacts
Public ContactPornchai Jansisyanont
Faculty of Dentistry, Chulalongkorn University
Outcome results
None listed