Exercise in cirrhosis Excercise in cirrhosis,
Conditions
Interventions
Home base exercise program ,Non home base exercise
Experimental Other,Placebo Comparator Other
Home base excercise,Placebo (non home base excercise)
Sponsors
Siriraj Medical Research Center(SiMR)
Gastroenterological Association of Thailand(GAT)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 year old 2. Cirrhosis Child Turcotte Pugh score 13 kPa 3 The cause of cirrhosis - Chronic hepatitis B with HBV DNA viral load < 10 IU/ml) - Chronic hepatitis C with sustain virological response (SVR) - Alcoholic cirrhosis with alcohol abstinence for 1 year - Nonalcoholic steatohepatitis
Exclusion criteria
Exclusion criteria: 1.BMI > 28 kg/m2 2.Esophageal varices(EV) > F2 or history of EV bleeding 3.Gastric varices 4.Coronary artery disease, cardiac arrhythmia, Ejection fraction 1 mm ST segment depression) 5.ESRD on renal replacement therapy 6.Active malignancy within 6 months 7.Myopathy 8.Severe asthma or COPD 9.Hb 7 more than 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effects of 12 weeks home-base exercise training on aerobic capacity Before and after 6 minute walk test | — |
Secondary
| Measure | Time frame |
|---|---|
| The effects of 12 weeks home-base exercise on muscle mass, portal HT and quality of life before and after US quadricep and circumference Rt leg, QoL questionnaire, fibroscan of liver and spleen | — |
Countries
Thailand
Contacts
Public ContactWatcharasak Chotiyaputta
SIMR
Outcome results
None listed