periodontitis periodontal pocket clinical attachment loss inflammatory cytokines Nd:YAG laser Smoking periodontitis periodontal pocket biostimulation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: good general health patient having at least 12 natural teeth with minimum of three in each jaw quadrant. Two sites in each quadrant with a minimum probing depth of 5mm. smoking at least ten cigarettes per day.
Exclusion criteria
Exclusion criteria: pregnancy lactation systemic antibiotic use or periodontal treatment within the the past 6 months. antienflamatuar medication use within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical attachment level baseline, 30 days, 3 months measured using a manual periodontal probe | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical markers ( Il-1B, TNF-a, MMP-8) baseline, 30 days, 3 months Enzym linked immunoabsorbant assay | — |
Countries
Turkey
Contacts
Department of Periodontics, Faculty of dentistry