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Analgesic efficacy of a single-dose intraoperative intraarticular morphine in ACL Reconstruction

Analgesic efficacy of a single-dose intraoperative intraarticular morphine in ACL Reconstruction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190903004
Enrollment
Unknown
Registered
2019-09-03
Start date
2017-12-18
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior cruciate ligament injury Anterior cruciate ligament ACL reconstruction Morphine Intraarticular

Interventions

15 mg Intra&#45
articular morphine in 20 ml NSS,20 ml NSS
Experimental Drug,Placebo Comparator No treatment
articular morphine,Control

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria in this study consisted of patients aged between 18-40 years, who were supposed to undergo ACL reconstruction surgery.

Exclusion criteria

Exclusion criteria: The exclusion criteria were the patients who refuse to participate in the study, patients with other knee ligaments, patients with a history of knee surgery, patients with a history of opioid allergy, patients with a history of drug addiction, patients who received any anesthesia or postoperative analgesia different from our protocol.

Design outcomes

Primary

MeasureTime frame
Time to the first rescue medication (IV Morphine) first analgesic request by patient Time record

Secondary

MeasureTime frame
Post-operative pain score 6, 12, 18 and 24 hours postoperatively Visual analogue scale (VAS),Post-operative Complication (from Morphine) until discharge None

Countries

Thailand

Contacts

Public ContactSuthee Tharakulphan

Khon Kaen hospital, Thailand

Oe_orthokkh@hotmail.com+66850608561

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026