Surgical wound infiltration of Multimodal analgesia compared with local anesthetic for reduce post-operative pain in MIS TLIF : A randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190829001

Enrollment

Registered

2019-08-29

Start date

2019-08-30

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients under going MIS TLIF one level

Interventions

The drugs in multimodal group consist of 0.5% bupivacaine 92.5 mg (18.5ml.) Ketorolac 30mg (1ml.) Morphine 5mg (0.5ml.) & adrenaline 0.5mg (0.5ml) 10 ml. into facet joint before incision 10 ml. Into s

subcutaneous & thoracolumbar fascia at the end of operation ,The drugs in control group consist of 0.5% bupivacaine 100 mg (20ml.) & adrenaline 0.5mg (0.5ml) 10 ml. into facet joint before incision 10

subcutaneous & thoracolumbar fascia at the end of operation

Experimental Drug,Experimental Drug

Multimudal group,Control group

Eligibility

Sex/Gender

All

Age

20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Pt. under going MIS TLIF 1 level Age 20-80 years Good mental status Complete inform & consent

Exclusion criteria

Exclusion criteria: Allergy or contraindication to any drugs in this study Impair renal and/or hepatic function Other comorbid pain condition

Design outcomes

Primary

Measure	Time frame
Post-operative Pain score at 3, 6, 12, 24 hrs 3, 6, 12, 24 hrs post-operation Visual analog scale	—

Secondary

Measure	Time frame
Post-operative morphine consumption 24 hrs post-operatively Observe among of morphine that patient required,Blood loss in close suction drain until drain is removed Observe in close suction drain,Morphine related side effect 24 hrs post-operatively Patient reported,Time to ambulation Post-operative until ambulation Observe when patient start to ambulation with/without walker,Length of hospital stay Post-operative until discharge Medical record	—

Measure

Time frame

Post-operative morphine consumption 24 hrs post-operatively Observe among of morphine that patient required,Blood loss in close suction drain until drain is removed Observe in close suction drain,Morphine related side effect 24 hrs post-operatively Patient reported,Time to ambulation Post-operative until ambulation Observe when patient start to ambulation with/without walker,Length of hospital stay Post-operative until discharge Medical record

—

Countries

Thailand

Contacts

Public ContactTodsapon Chancharoenchai

Orthopedics department, Faculty of medicine, Chulalongkorn university

animale.ruby@gmail.com0868666446

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Surgical wound infiltration of Multimodal analgesia compared with local anesthetic for reduce post&#45;operative pain in MIS TLIF : A randomized controlled trial.