Acute effect of stevia ingestion on glycemic and insulin responses in obese patients Stevia,
Conditions
Interventions
Obese patients underwent a 75 gram oral glucose tolerance test (OGTT) preceded by consuming pills containing either 200 mg stevia or placebo for 60 minutes before test on two separate occasions,
1 week apart,
in a randomized crossover design. Blood samples were obtained for glucose and insulin at 0,
90 and 120 minutes,Empty capsule
Experimental Dietary Supplement,Placebo Comparator No treatment
Stevia,Placebo
Sponsors
The Endocrine Society of Thailand
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age ≥ 18 years BMI ≥ 25 kg/m2 Informed consent
Exclusion criteria
Exclusion criteria: Diabetes Mellitus HIV, malignancy, pregnancy Chronic liver disease eGFR <30 mL/min/1.73 m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin indicies 0,30,60,90 and 120 minutes after 75 gram glucose ingestion Matsuda index, Insulinogenic index, Disposition index | — |
Secondary
| Measure | Time frame |
|---|---|
| Area under the curve 0,30,60,90 and 120 minutes after 75 gram glucose ingestion Area under the curve of Insulin and glucose response | — |
Countries
Thailand
Contacts
Public ContactParinya Samakkarnthai
The Endocrine society of Thailand
Outcome results
None listed