Xerostomia patients head and neck cancer, moistening, post-radiotherapy, quality of life, Trehalose, xerostomia
Conditions
Interventions
newly-offered oral spray for oral moisturising ,Previously-reported formula oral spray
routinely prescribed at Chulalongkorn Hospital post radiotherapy
Trehalose-based oral spray),CMC-based oral spray
Sponsors
Graduate school Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: The patients aged 18 years or older, and cooperatively follow home instructions. Patients previously completed radiotherapy for at least 1 month before enrollment. The fields of radiation encompassing the major and minor salivary glands, unilaterally or bilaterally. Patients who received bilateral Intensity Modulated RT (IMRT) were included if they completed the RT within 12 months before enrollment.
Exclusion criteria
Exclusion criteria: Patients with Sjogren's syndrome or other salivary gland diseases Uncooperative patients Patients on feeding tube
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Xerostomia quality of life score 2 weeks later after used intervention questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| salava flow rate and pH of saliva 2 weeks later after used intervention volume of unstimulated saliva in 5 mins | — |
Contacts
Public ContactAnjalee Vacharaksa
Chulalongkorn University
Outcome results
None listed