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Analgesic efficacy of femoral nerve block on intraoperative fentanyl consumption for endovenous radiofrequency ablation and phlebectomy of varicose veins: A Randomized controlled study

Analgesic efficacy of femoral nerve block on intraoperative fentanyl consumption for endovenous radiofrequency ablation and phlebectomy of varicose veins: A Randomized controlled study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190808005
Enrollment
48
Registered
2019-08-08
Start date
2019-07-18
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Varicose veins Varicose vein postoperative pain femoral nerve block

Interventions

Comparison of different dosages of fentanyl Comparison of intraoperative and postoperative pain,Comparison of different dosages of fentanyl Comparison of intraoperative and postoperative pain
Active Comparator Drug,Active Comparator Drug
fentanyl,ultrasound guided femoral nerve block with 1 % lidocaine with epinephrine ( 1:200&#44
000) 15 ml

Sponsors

Faculty of medicine, Siriraj hospital, Mahidol university
Lead Sponsor
Faculty of medicine&#44
Collaborator
Siriraj hospital&#44
Collaborator
Mahidol university
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: varicose veins at anteromedial side of leg

Exclusion criteria

Exclusion criteria: 1. refusal to participate in research 2. weight under 45 kgs. 3. allergy to fentanyl 4. uncontrolled diabetes 5. poor controlled of diabetes 6. contraindication of femoral nerve block 7. cognitive impairment or psychiatric problems 8. neurological deficit at legs 9. use of more than 20 mg of oral morphine for chronic pain

Design outcomes

Primary

MeasureTime frame
Total dose of fentanyl during surgery The end of operation Dose of fentanyl

Secondary

MeasureTime frame
Total dose of analgesic medication 24 hours after the end of operation dose of analgesic medication,Motor blockade of the quadriceps femoris 1 hour after finish operation The grading of quadriceps femoris strength,Postoperative pain at rest and on movement intraoperative, PACU, 6 hours after finish the operation, 12 hours after finish the operation Visual analogue scale,Time to first rescue analgesia dose after finish the operation 24 hours after finish the operation Minutes,Local anesthetic systemic toxicity 24 hours after finish the operation yes/no

Countries

Thailand

Contacts

Public ContactNaruenart Lomarat

Faculty of medicine, Siriraj hospital, Mahidol university

nong075@gmail.com092-639-5596

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026