skin rash,
Conditions
Interventions
Centella cream is an herbal preparation in the national list of essential drugs of Thailand and the list of herbal drugs of Chao Phya Abhaibhubejhr Hospital,
Prachinburi. The product was performed by Chao Phya Abhaibhubejhr Hospital Foundation and was GMP-
PIC/s certified. CA cream is comprised of 70% alcohol extract of CA (7% w/w) according to the national list of essential medicines.
Centella cream is white in color.
Usage: Participants will receive
appearance in white color and filled in the same package as Centella cream.
Usage: Participants will receive the standard treatment and are acquired to apply Placebo cream on the rash twice daily for
Active Comparator Drug,Placebo Comparator Drug
Centella Cream,Placebo or base cream
Sponsors
Thammasat University
Chao Phraya Abhaibhubejhr Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1 Male and female 2 Age of 1-17 years old 3 Patients have been diagnosed as atopic dermatitis by pediatric doctor 4 Atopic dermatitis patients with mild to moderate severity (SCORAD score < 40) 5 Onset not more than 6 months 6 Willing to participate in the trial
Exclusion criteria
Exclusion criteria: 1 History or presence of skin cancer of suspicious lesions 2 Participate in another study within the previous 4 weeks. 3 Allergy or sensitivity to CA or herbs in the family of Apiaceae 4 Applied any moisturizer on the skin lesions Discontinuation criteria 1 Skin lesions flare-up in the volunteers (SCORAD score more than 40) 2 Secondary infection on-top to the skin 3 The occurrence of any severe adverse event 4 Applied any moisturizer on the skin lesions 5 Loss follow up more than 1 visit, or at the last week 6 Loss of follow up more than 1 appointment and at week 4 7 Do not desire to continue the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the severity of Atopic dermatitis 4 weeks SCORAD Score | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety 4 weeks patient's interview, Naranjo algorithm ,Quality of life 4 weeks IDQOL/CDLQI | — |
Countries
Thailand
Contacts
Public ContactNutcha Tengtermwong
Chao Phraya Abhaibhubejhr
Outcome results
None listed