Diabetes Mellitus Diabetes Mellitus Anthocyanins Inulin Dietary Fiber Oxidative Stress Inflammation Insulin Resistance Fat Oxidation Cardiovascular Function
Conditions
Interventions
Dietary Supplement Containing a Mixtures of Anthocyanins,
Inulin and Fiber Capsule as Intervention Group,Maltodextrin Powder will be Contained into Each Capsule for Using as Placebo
Experimental Dietary Supplement,Placebo Comparator No treatment
Anthocyanins,
Inulin and Fiber Capsule ,Placebo Capsule
Sponsors
National Research Council of Thailand
Exercise and Sport Sciences Development and Research Group,
Khon Kaen University
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Subjects are male and female patients aged 30-60 years who are diagnosed with type 2 diabetes mellitus (T2DM) longer than 1 year. 2. Subjects who sign the consent form and can participate in the study until the end of project.
Exclusion criteria
Exclusion criteria: 1. Subjects with liver, kidney and thyroid diseases. 2. Subjects with respiratory tract diseases including asthma and chronic obstructive pulmonary disease (COPD). 3. Subjects with cardiovascular disease including heart failure and coronary artery disease (CAD). 4. Subjects with symptoms associated with neuromuscular disorders such as dizziness, nausea, vomiting, osteoporosis, muscle weakness and spinal stenosis. 5. Subjects with chronic infection. 6. Subjects who regularly drink alcohol or smoking. 7. Subjects who take hormones or nutritional supplements regularly. 8. Subjects who were reported that allergy to the ingredients of dietary supplements used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Malondialdehyde (MDA) Concentration (Oxidative Stress) 1 day Colorimetry based method,Vitamin C Level (Oxidative Stress) 1 day Colorimetry based method | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin (IL)-6 Level (Inflammation) 1 day Assay Kit,Insulin Resistance 1 day HOMA-IR will be Used to Assess Insulin Resistance, and will be Calculated by the Formula ,Fat Oxidation Rate 1 day Using Gas Analyzer and Calculate Fat Oxidation Rate by Using the Equation,Maximal Oxygen Consumption (VO2max) (Cardiovascular Function) 1 day 6 Minutes Walk Test (6MWT) with Moderate Intensity,Blood Vessel Thickness (Cardiovascular Function) 1 day Skin Ultrasound Examination,Heart Rate Variability (HRV) Assessment (Cardiovascular Function) 1 day Using SA-3000P HRV analyzer | — |
Contacts
Public ContactChompoonut Teparak
Graduate School, Khon Kaen University
Outcome results
None listed