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EFFECT OF KETAMINE ON EMERGENCE AGITATION FOLLOWING SEPTOPLASTY

EFFECT OF KETAMINE ON EMERGENCE AGITATION FOLLOWING SEPTOPLASTY

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190729001
Enrollment
Unknown
Registered
2019-07-29
Start date
2018-07-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergence agitation postoperative cough Emergence agitation&#44

Interventions

After monitoring peripheral capillary oxygen saturation&#44
non&#45
invasive blood pressure&#44
heart rate (HR) and bispectral index (BIS)&#44
induction was performed with 2.5 mg/kg propofol&#44
2 mcg/kg fentanyl and 0.6 mg/kg rocuronium&#44
and the patients were intubated. Anaesthesia was maintained by administering a mixture of 50% oxygen and 5%–7% desflurane in air at a flow rate of 2 L/min with 0.05–0.5 mcg/kg/min remifentanyl inf
tidal CO2 level between 30 and 35. Immediately after induction&#44
20 mL normal saline containing 1 mg/kg ketamine was intravenously administered. Postoperative sedation/agitation level at emergence&#44
incidence of cough were recorded. Vital signs and sedation/agitation and pain levels were recorded at 10&#45
min intervals for 30 min in the recovery unit.,After monitoring peripheral capillary oxygen saturation&#44
tidal CO2 level between 30 and 35.20 mL normal saline was intravenously administered in 10 min. Postoperative sedation/agitation level at emergence&#44
incidence
Experimental Drug,Placebo Comparator No treatment

Sponsors

none
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA 1-2 septoplasty patients

Exclusion criteria

Exclusion criteria: Patients with a history of ketamine allergy, hypertension, coronary artery disease, arrhythmia, seizure, obstructive sleep apnoea, glaucoma, kidney disease and liver disease as well as those with a body mass index of >30 kg/m2 and cognitive dysfunction were excluded from the study.

Design outcomes

Primary

MeasureTime frame
effect of ketamine on emergence agitation after septoplasty emergence period and during postoperative 30 minutes Riker Sedation/Agitation Scale ,incidence of emergence agitation after septoplasty emergence period and during postoperative 30 minutes Riker Sedation/Agitation Scale—

Secondary

MeasureTime frame
effect of ketamine on cough emergence period 4-point scale—

Contacts

Public ContactSüheyla Abitağaoğlu

Fatih Sultan Mehmet Health Application and Research Center

suheylaatay81@gmail.com+905325267656

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026