To explore the ability of probiotic Lacidophilin Vaginal Capsules plus Clotrimazole Vaginal Tablets (500mg) in improving the treatment of uncomplicated vulvovaginal candidiasis (VVC)
Conditions
Interventions
Women with uncomplicated VVC were treated with 500mg single dose of Clotrimazole Vaginal Tablet plus a 7-
day regimen of Lacidophilin Vaginal Capsules (2 tablets per day).
Active Comparator Drug
Clotrimazole plus probiotic Lacidophilin Vaginal Capsules
Sponsors
Ruifang An
Xianling Zeng
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1)20-50 years old with a history of sexual life; (2) diagnosis of uncomplicated VVC or normal vaginal microflora; (3) regular menstruation ends for at least 3 days, no vaginal irrigation or drug delivery in the vagina within 7 days and no sexual intercourse within 3 days before examination.
Exclusion criteria
Exclusion criteria: Exclusion criteria: Women who had mixed vaginitis; women who was in the period of pregnancy, menstruation or lactation; women who had hysterectomy or bilateral excision of the appendix. Besides, patients with incomplete medical record were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sequencing results 1 month after the operation 16S rDNA sequencing | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjects’ demographics 1 month after the operation Clinical observations within 1 month after the operation | — |
Countries
China
Contacts
Public ContactRuifang An
Xi’an Jiaotong University
Outcome results
None listed