Chronic rhinosinusitis Initial treatment Corticosteriod nasal spray Corticosteroid nasal irrigation Chronic rhinosinusitis Initial treatment Corticosteriod nasal spray Corticosteroid nasal irrigation Before sinus surgery
Conditions
Interventions
Group 1 (budesonide spray group) patients were treated with a 250 mL normal saline irrigation and 64 mcg budesonide nasal spray twice daily.,Group 2 (budesonide irrigation group) were treated twice da
volume 250 mL budesonide irrigation (budesonide 1 mg nebulizer suspension in normal saline solution 500 mL divided into two doses).
Experimental Device,Experimental Device
Budesonide nasal spary ,Budesonide nasal irrgation
Sponsors
none
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients who were older than 18-years-old and who had been diagnosed with CRS without nasal polyps.
Exclusion criteria
Exclusion criteria: Patients who had already undergone sinus surgery, used systemic or topical corticosteroid in the past one month, used immunosuppressive drugs, were pregnant, had underlying cystic fibrosis, and patients who were unable to meet the follow-up requirements of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS, SNOT-22 3 months numerical | — |
Secondary
| Measure | Time frame |
|---|---|
| Lund-Kenedy endoscopic score 3 months numerical | — |
Contacts
Public ContactBoonsam Roonpuvapaht
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed