Osteoarthritis of the knee (OA Knee) OA Knee Osteoarthritis of the knee TKA Total knee arthroplasty TKR Total knee replacement IPACK Interspace between the popliteal artery and the capsule of the posterior knee ACB Adductor cana
Conditions
Interventions
Interspace between the popliteal artery and the capsule of the posterior knee (IPACK) block plus standard pain control regimen (adductor canal block + periarticular injection),Only standard pain contr
IPACK Block,No IPACK Block
Sponsors
Faculty of Medicine Siriraj Hospital
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients age >50 years old who undergo elective unilateral primary TKA
Exclusion criteria
Exclusion criteria: -Contraindications to spinal anesthesia and/or regional nerve block -Allergy to ketolorac or etoricoxib (NSAIDs used in the study) -Previous knee surgery -Patients with severe medical condition; ASA class IV or more -Renal impairment (CrCl < 50 ml/min) -Patients with severe cognitive impairment -Diseases which limit lower extremity function -Non-ambulatory patient -Patients with chronic pain in other parts of body that are under treatment with chronic pain service team -Patient refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score on Numeric Rating Scale (NRS) at rest at POD 1 Post-operative day 1 Pain score | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score on NRS at rest/during ambulation at PO day 0-3, 2wk, 6wk PO day 0-3, 2wk, 6wk Pain score,Knee ROM PO day 0-3, 2wk, 6wk Degree,Opioid consumption PO day 0-3 Dose,Time to first dose of analgesia Time to first dose of analgesia Hour,Ambulatory status PO day 3 Ambulation with or without gait aid | — |
Countries
Thailand
Contacts
Public ContactSwist Chatmaitri
Faculty of Medicine Siriraj Hospital
Outcome results
None listed