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The Efficacy of Vitamin C vaginal suppository for the Treatment of postmenopausal Vaginal Atrophy A Randomized Controlled Trial

The Efficacy of Vitamin C vaginal suppository for the Treatment of postmenopausal Vaginal Atrophy A Randomized Controlled Trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190712001
Enrollment
Unknown
Registered
2019-07-12
Start date
2019-07-11
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the most bothersome vaginal symptoms the most bothersome vaginal symptoms

Interventions

vitamin C 500 mg vaginal suppository every day until 12 day then twice a week,placebo drug vaginal suppository every day until 12 days then twice a week
Active Comparator Drug,Placebo Comparator Drug

Sponsors

khon kaen university
Lead Sponsor
khon kaen university
Collaborator

Eligibility

Sex/Gender
Female
Age
45 Years to 100 Years

Inclusion criteria

Inclusion criteria: - postmenopausal women aged over 45 years - vaginal dryness/soreness score more than or equal to 4

Exclusion criteria

Exclusion criteria: - Women who received hormone replacement therapy - Women who use vaginal suppositories to treat other conditions within 1 week - Women with a history of hypersensitivity to vitamin C components - Women who use herbs or other health supplements - Women who had received pelvic radiation - Women with severe symptoms (vaginal dryness/soreness score more than 8)

Design outcomes

Primary

MeasureTime frame
mean score of vaginal dryness/soreness 4 weeks Visual analog score

Secondary

MeasureTime frame
vaginal maturation index 4 week cytology

Countries

Thailand

Contacts

Public Contactnisanat booning

-

tobee_b@hotmail.com0867199139

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026