Inhibitory effect of proretinal nanoparticle on sebum production on facial skin: a randomized, double-blind, placebo-controlled trial

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190709002

Enrollment

Registered

2019-07-09

Start date

2019-08-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

seborrhea seborrhea

Interventions

gel contains proretinal nanoparticles as an active ingredient.,gel without proretinal nanoparticle

Experimental Drug,Placebo Comparator Drug

proretinal nanoparticle gel,placebo

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: seborrhea

Exclusion criteria

Exclusion criteria: -subjects who have known allergy or sensitivity to skincare products -subjects who receive topical retinoids within 1 month. -subjects who receive oral isotretinoin, spironolactone, oral contraceptives or any anti-androgenic drugs within 3 months. -pregnant or lactating women

Design outcomes

Primary

Measure	Time frame
Sebum content weeks 0,1,2,3,4 multi-probe adapter system Cutometer dual MPA580	—

Secondary

Measure	Time frame
transepidermal water loss weeks 0,1,2,3,4 multi-probe adapter system Cutometer dual MPA580	—

Countries

Thailand

Contacts

Public Contactchanat kumtornrut

Faculty of Medicine, Chulalongkorn University

chanat_1@yahoo.com0814594965

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026