Advance Cholangiocarcinoma -
Conditions
Interventions
Endobiliary radiofrequency ablation prior to Biliary metal stent,Biliary metal stent only
EBRFA,Biliary stent
Sponsors
Khon Kaen University
Faculty of medicine ,Faculty of medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-75 years old. 2. Unresectable or recurrent cholangiocarcinoma diagnosis by pathology or radiographic. 3. Obstrucvtive jaundice (Total bilirubin > 3 mg/dl.) 4. Aviable for ERCP and Percutaneous procedure.
Exclusion criteria
Exclusion criteria: 1. Massive ascites. 2. Uncorrectable coagulopathy. 3. Presence of main portal vein thrombosis. 4. Prior SEMS placement. 5. Child-Pugh Score C cirrhosis. 6. Pregnancy. 7. Performance status ECOG ≥ 3 (confined to bed / chair > 50% waking hours). 8. Presence of other malignancy. 9. Life expectancy 1.5)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patency rate of biliary stent Date of procedure to Date of stent obstruction Evidence of stent obstruction : Rising of Total bilirubin | — |
Secondary
| Measure | Time frame |
|---|---|
| Survival Date of procedure to death Follow up until patient die or end of study | — |
Countries
Thailand
Contacts
Public ContactNarong Khuntikeo
Cholangiocarcinoma research institute
Outcome results
None listed