Osteoarthitic knee pain osteoarthritic knee,
Conditions
Interventions
Patients that allocated in this group will receive a genicular nerve ablation under ultrasound guidance.,Patients that allocated in this group will receive a genicular nerve ablation under fluoroscopi
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
genicular nerve ablation under ultrasound-
guided,genicular nerve ablation under fluoroscopic-
Sponsors
Faculty of medicine, Siriraj hospital funding
Routine to research unit,
Siriraj hospital
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >50 years with knee osteoarthritis including the following criteria: - pain score >=4 from osteoarthritis - malalignment of knee - plain film of the knee showed stage 3 or 4 of knee osteoarthritis - not proceed to surgery within 1 year 2. Failed conservative treatment over 2 months (quadricep exercise, weight control, life style modification, analgesic medications)
Exclusion criteria
Exclusion criteria: 1. Coagulopathy or bleeding disorder, systemic infection, infection around knee 2. Currently receiving the treatment of intraarticular visco-supplement injection 3. Connective tissue disease that involved skin around knee joints 4. On pacemaker 5. Unknown history of previous treatment 6. Uncontrolled psychiatric diseases (schizhrophrenia, major depressive disorder, generalized anxiety disorder) 7. Negative diagnostic block
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain score 3 month after an intervention numerical rating scale,pain score 1 month after an intervention numerical rating scale | — |
Secondary
| Measure | Time frame |
|---|---|
| pain score 1 years numerical rating scale,Function of knee 4, 12, 26, 38, 52 weeks Thai Oxford Knee score (Thai OKS), Thai KOOS short form (Thai KOOS SF), Time up and go test (TUG tes,analgesic drug consumption 4, 12, 26, 38, 52 weeks Baseline pain medication, Rescue pain medication ,range of motion of knee 4, 12, 26, 38, 52 weeks Range of motion (ROM) of the knee,quality of life 4, 12, 26, 38, 52 weeks EuroQoL 5D-5L (Thai version),Inflammation process 0, 4, 12 weeks ESR and hs-CRP blood level,safety of genicular nerve ablation 0, 4, 12, 26, 38, 52 weeks Side effects and complications, Fall evaluation | — |
Countries
Thailand
Contacts
Public ContactPramote Euasobhon
Faculty of Medicine Siriraj hospital, Mahidol university
Outcome results
None listed