FindTrial
Sign In

A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study on the effectiveness of cash-based reinforcement therapy on craving in Ecstasy/MDMA users, the mediator role of depression

A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study on the effectiveness of cash-based reinforcement therapy on craving in Ecstasy/MDMA users, the mediator role of depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190628001
Enrollment
Unknown
Registered
2019-06-28
Start date
2015-02-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

craving of Ecstasy/MDMA use and depression cash&#45

Interventions

In a Pilot Study&#44
during the February to October 2015&#44
among the population of female Ecstasy users living in Tehran&#44
during the abstinence process (< 4 weeks)&#44
25 dysthymic patients and 29 patients without dysthymic diagnosis were eligible to intervention procedure. CBRT was presented to both groups for a period of twelve weeks with incentives worth of $0&#
$15&#44
$20&#44
and $30). The case manager’s estimated that total annual compensation was $1&#44
332 ($6.24 per hour). The average cost of supplies and reinforcers was $61 (3). Urine specimen validity was investigated by immunochromatography (ICG) with a threshold of 500 ng/ml. To analyze the dat
generalized estimating equations (GEE) and repeated measures correlation (rmcorr) were used by IBM SPSSS statistics Version 20 (SPSS&#44
Inc.&#44
Chicago&#44
IL&#44
USA).
Experimental Behavioral
Cash&#45
based reinforcement therapy

Sponsors

None listed

Eligibility

Sex/Gender
Female
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1) women patients&#44; age range of 18 to 30 years&#44; 2) read and understood Persian&#44; 3) Fulfilling DSM&#45;IV diagnostic criteria for Ecstasy dependence and seeking treatment At during Abstinence from Ecstasy/MDMA (≥3 week) and Taking at least one and up to three ecstasy tablets within thirty days prior to abstinence.

Exclusion criteria

Exclusion criteria: Being psychotic or bipolar&#44; having gambling disorders (because of potential similarity of prize&#45;oriented CM with gambling)&#44; 2) current physical dependence on alcohol or sedatives&#44; 3) having an unstable serious medical illness and having Convulsive seizures&#44; acute hyponatremia and hyperthermia affecting the kidneys 4) having an IQ below 80.

Design outcomes

Primary

MeasureTime frame
Craving 12 weeks Craving questionnare—

Secondary

MeasureTime frame
depression 12 weeks Beck Depression Inventory (BDI)—

Countries

iran

Contacts

Public Contactbijan pirnia

Bijan Center for Substance Abuse Treatment&#44; tehran&#44; iran

b.pirnia@usc.ac.ir+9802122081450

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026