Periodontal disease is the most common oral disease leads to soft tissue and alveolar bone destruction. Diabetes mellitus increase risk of periodontitis. Periodontitis Cathepsin K Gingival crevicular fluid
Conditions
Interventions
healthy patients
Basic Science
Control
Sponsors
Faculty of Dentistry, Mahidol university
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with chronic periodontitist 2. more than 30 percent of site with probing depth more than 5 mm with gingival inflammation
Exclusion criteria
Exclusion criteria: 1.Any systemic disease that effect progression and healing periodontal disease or have to take antibiotic premedication 2.On medication that effect to periodontium
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cathepsin K baseline, 3 months from baseline, 3 years from baseline picograms/enzyme-linked immunosorbent assay ,Cathepsin K concentration baseline, 3 months from baseline, 3 years from baseline picograms per microlitre /enzyme-linked immunosorbent assay | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing depth baseline, 3 months from baseline, 3 years from baseline millimetre/PCPUNC 15, Hu-Friedy,Clinical attachment level baseline, 3 months from baseline, 3 years from baseline millimetre/PCPUNC 15, Hu-Friedy | — |
Countries
Thailand
Contacts
Public ContactAuttaporn Chaisalee
Department of Oral Medicine and Periodontology, faculty of dentistry mahidol university, No. 6, Yoth
Outcome results
None listed