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Efficacy of double dose influenza vaccine with a booster compare to standard dose in hemodialysis patients ; randomized controlled trial

Efficacy of double dose influenza vaccine with a booster compare to standard dose in hemodialysis patients ; randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190620001
Enrollment
100
Registered
2019-06-20
Start date
2019-06-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergy to component of vaccine

Interventions

Quavalent influenza vaccination 2 doses then 1 dose next 2 week Collection of hemaglutination titer for influenza 4 strains before first vaccination and next 2&#44
4 week,Quavalent influenza vaccination 1 dose Collection of hemaglutination titer for influenza 4 strains before first vaccination and next 2&#44
4 week
Experimental Drug,Active Comparator Drug
Double dose influenza vaccine with a booster,Standard dose influenza vaccine

Sponsors

Goverment
Lead Sponsor
Goverment
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patients undergoing hemodialysis OPD at BAH Age ≥ 18 years Sp Kt/V ≥ 1.2 Hb ≥ 9 g/dL Serum albumin ≥ 3 g/dL Serum ferritin < 1&#44;000 ng/mL

Exclusion criteria

Exclusion criteria: Immunocompromised host e.g. HIV Taking any immunosuppressive agent for 3 months subsequent months before enrollment Having been hospitalized for 3 months subsequent months before enrollment

Design outcomes

Primary

MeasureTime frame
Number of patients with seroprotection of influenza infection Before vaccination&#44; 2 weeks and 4 weeks after vaccination Hemoagglutination inhibitor titer for influenza 4 strains

Secondary

MeasureTime frame
Seroprotection and seroconversion 4 weeks after first vaccination Hemoagglutination inhibitor titer for influenza 4 strains

Countries

Thailand

Contacts

Public ContactEkapol Ritveeradej

Bhumibol Adulyadej hospital

Mega9926@hotmail.co.th0840772093

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026