Healthy Thai subjects aged between 30-
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy both male or female aged between 30-65 years old 2. All skin types 3. Having clear visible wrinkle at eye corner and forehead 4. having experience using a counter brand facial skin care 5. No wound, scar or any skin disease on the face 6. No smoking, drinking or drug abuse history 7. No allergic history of ingredient in the anti-wrinkle product 8. Be able to read, communicate and write Thai language 9. Be able to not use other anti-wrinkle and moisturizer product during the 8 weeks study 10. Having consent in the study after be informed objective, methodology possible risk and result, and be able to follow the study protocol 11. Willing to sign informed consent form after be provided information related and possible output during the study, and volunteer are able to ask any additional information except trade secret
Exclusion criteria
Exclusion criteria: 1. Having history of eczema, psoriasis within 6 months before enroll the study 2. Having history of using steroid, antibiotic, NSAIDs and antihistamine within 3 days before enroll the study 3. Having history of topical medicine uses on the face within 3 weeks before enroll the study 4. Having underlying diseases and taking continuous medicines 5. Having history of major operation within 1 year 6. Having history of skin cancer within 1 year 7. Having pregnancy or lactation 8. Being or having experience in participating other clinic
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin hydration week 0, 2, 4, 6, 8 Corneometer,Skin roughness and wrinkle week 0, 2, 4, 6, 8 PRIMOS lite,Facial photograph of the crow's feet area week 0, 2, 4, 6, 8 Canon EOS Rebel T5i 700D,Diary of product uses week 0, 2, 4, 6, 8 Diary,Self-assessment after week 8 Questionnaire form | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Cosmetics and natural products research center, Faculty of Pharmaceutical Sciences, NU