The study population will be consisted of three groups: one group will be COPD group another group will be non-
Conditions
Interventions
Suspected COPD subjects aged ≥ 40 years old with history of smoking 10 packs-
year.
,Healthy subjects aged ≥ 40 years old with no history of chronic respiratory diseases,
non-
smokers or ex-
smoker < 5 packs-
year,
and normal spirometry.
Diagnostic,Diagnostic
Suspected COPD,Healthy control
Sponsors
Faculty of Medicine, Chiang Mai University
Department of Internal Medicine,
Faculty of Medicine,
Chiang Mai University
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Suspected COPD group - Suspected COPD subjects aged ≥ 40 years old - No history of chronic respiratory diseases other than COPD - Smokers or ex-smoker ≥ 10 packs-year 2. Healthy control - Healthy subjects aged ≥ 40 years old - No history of chronic respiratory diseases - Non-smokers or ex-smoker < 5 packs-year - Normal spirometry
Exclusion criteria
Exclusion criteria: Exclusion criteria: The study population will be excluded from the study according to the following criteria: - Unable to perform spirometry - Unable to perform IOS - Spirometry not met American Thoracic Society (ATS)/European Respiratory Society (ERS) 2005 standard - IOS not met standard recommended by Bickel et al and ERS standard
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cut off point of IOS parameter for diagnosis COPD 0 min cmH2O | — |
Secondary
| Measure | Time frame |
|---|---|
| ROC curve of IOS parameter for diagnosis COPD 0 min percent | — |
Countries
Thailand
Contacts
Public ContactChaicharn Pothirat
Faculty of Medicine, Chiang Mai University.
Outcome results
None listed