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Effectiveness of Antibiotic Prophylaxis in Patients with Centipede bites: a randomized control trial

Effectiveness of Antibiotic Prophylaxis in Patients with Centipede bites

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190613005
Enrollment
90
Registered
2019-06-13
Start date
2014-12-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

&#45

Interventions

Capsules of 250&#45
milligram dicloxacillin 4 times a day&#44
after meals for 5 days.,The capsules being identical in appearance 4 times a day&#44
after meals for 5 days.
Experimental Drug,Placebo Comparator Drug
Dicloxacillin,Placeblo

Sponsors

Faculty of Medicine, Chaing Mai University
Lead Sponsor
Faculty of Medicine&#44
Collaborator
Chaing Mai University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - 18 years old or above - Had been bitten by a centipede within 12 hours of arriving at the emergency department - Known the precise location of bite

Exclusion criteria

Exclusion criteria: - Allergic to penicillin and those who had taken antibiotics within the 7 days prior to admission. - Immunocompromised such as patients with poorly controlled DM, undergoing chemotherapy, leukemia or cancer, HIV positive, humoral immune deficiency, post splenectomy, using steroids. - Patients with severe infection, fever, wounds with water blisters, pus or necrosis needing surgical drainage, wounds showing a rapid spread of infection or with a clinical description matching necrotizing fasciitis

Design outcomes

Primary

MeasureTime frame
Wound infection in 5 day after centipedes bite increasing pain, swelling, red/burning sensation, tenderness, postulation or wound turning black

Secondary

MeasureTime frame
tongue coating Researcher record the data suddenly after intervention and 3 hours after intervention tongue coating index

Countries

Thailand

Contacts

Public ContactBorwon Wittayachamnakul

Faculty of Medicine, Chiang Mai University

borwonwitt@hotmail,com66866595780

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026