28 healthy asian female,
Conditions
Interventions
Fourteen subjects in the first group were received placebo sample,Fourteen subjects in the second group were assigned for the test sample
Control group,Test product group
Sponsors
Cerebos Pacific Limited
Eligibility
Sex/Gender
Female
Age
40 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Healthy female age 40-55 years 2. Having grade 2 or more wrinkles and grade 1-2 dyspigmentation (by photographic scale) 3. No smoking, alcoholic and drug addiction 4. Express willingness to cooperate eith the invesigator 5. Free will written consent of the volunteers
Exclusion criteria
Exclusion criteria: 1. History of acute or chronic disease such as severe liver of kidney disease, uncontrolled diabetes 2. Patient suffering from skin cancer 3. Medical or cosmetic treatment interfering with general ageing process for at least 3 months before study 4. Taking functional food 1 month before the study 5. History of allergies against any components of trial food or seafood 6. Pregnant of planing on become pregnant within 3 months or lacting female 7. Any visible skin disease which might be confuced with a skin reaction from the test procedure or materisl or interfere the measurement 8. Smoker and/or heavy drinker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin color 0, 4, 6, 8, 12 weeks of treatment Chromameter,Skin elasticity 0, 4, 6, 8, 12 weeks of treatment Cutometer,Skin barrier function 0, 4, 6, 8, 12 weeks of treatment Tewameter,Skin moisture 0, 4, 6, 8, 12 weeks of treatment Corneometer,Skin temperature 0, 4, 6, 8, 12 weeks of treatment Skin Thermometer,Skin micro-circulation 0, 4, 6, 8, 12 weeks of treatment Laser speckle,Urine Analysis after week 12 BUN, CRE, Micro-albumin, Ketone,Blood Analysis after week 12 CRP, LDL, Triglyceride, FBS | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactNeti Waranuch
Cosmetics and natural products research center, Faculty of Pharmaceutical Sciences, NU
Outcome results
None listed