Healthy Thai subjects
Conditions
Interventions
4 products for skin irritation test
-
Hydrogel sheet
-
Aloe vera coated hydrogel sheet
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Silver nanoparticles coated hydrogel sheet and CARISS Facial cream
-
CARISS Facial cream
Experimental Other
4 product skin irritation test
Sponsors
Thailand institute od Nuclear Technology (Public Organization) (Head Office)
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Healthy female and male volunteers of all skin types with an age range 20-60 years old 2. Free of wound, scar or any skin disease on the test area 3.Willing to participate in the study after being informed on objective, methodology, possible risk and expecting outcome of the study 4. Be able to read, write and communicate in Thai 5. Willing to sign consent of the volunteer
Exclusion criteria
Exclusion criteria: 1. History of hypersensitive skin 2. History of eczema or psoriasis within 6 months before the study 3. History of medical treatment with steroids, antibiotic, NSAIDs, anti-histamine within 3 days before the study 4. History of using topical medicine on the test area within 3 weeks before the study 5. Having any disease on the test area that required regular use of any topical medicine 6. History of major operation within 1 year 7. History of skin cancer within 1 year 8. Pregnancy or lactation 9. Heavy smoker or regular drink 10. History of addiction to any narcotic substances 11. History of all allergenic reaction to Aloe vera or Silver nitrate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin irritation test 0, 0.5, 1, 24h 24 hours patch test | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactNeti Waranuch
Cosmetics and natural products research center, Faculty of Pharmaceutical Sciences, NU
Outcome results
None listed