Healthy Thai subjects aged between 25-
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy male and female aged 25-55 years 2. Having clear visible wrinkle at eye corners and forehead 3. Having Fitzpatrick skin type III to V 4. Having normal, dry, oily as well as combination skin 5. Having experience using a counter brand skin care 6. No history of allergy problem to any commercial available anti-wrinkle and skin whitening products 7. Be able to read, communicate and write Thai language 8. Willing to participate in the project and be able to follow the study protocol 9. willing to give a written consent of the volunteer after informed the study detail
Exclusion criteria
Exclusion criteria: 1. Having wound, scar or any skin disease on the face 2. History of skin eczema, psoriasis within 6 months before enter the study 3.History of using steroid, antibiotic, NSAIDs and antihistamine within 3 days before enter the study 4. Having chronic disease and continuous taking medicines 5. History of major operation within 1 year before enter the study 6. History of skin cancer within 1 year before enter the study 7. Pregnancy or lactation 8. History of using any contraceptive hormones within 6 months before enter the study 9. Having experience i laser treatment on the face within 1 monthe befor enter the study 10. participating other clinical studies within last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin Hydration week 0, 2, 4, 6, 8 Corneometer,Skin Color Assessment week 0, 2, 4, 6, 8 Mexameter Mx18 and Chromameter CM700d,Skin Surface Topography Week 2, 4, 6, 8 PRIMOS system,Self-assessment Questionnaire after week 8 Questionnaire form | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Faculty of Pharmaceutical Science