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Efficacy determination on lightening and anti-wrinkle of HEVEANA Rejuvenate Intensive Brightening Cream and HEVEANA Rejuvenate Advanced Anti-wrinkle Serum

Efficacy determination on lightening and anti-wrinkle of HEVEANA Rejuvenate Intensive Brightening Cream and HEVEANA Rejuvenate Advanced Anti-wrinkle Serum

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20190606005
Enrollment
Unknown
Registered
2019-06-06
Start date
2018-07-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Thai female subjects

Interventions

32 subjects completed the 8&#45
weeks study. Effect of the product on skin properties during 8 weeks of study were measured using various non&#45
invasive biophysical techniques.
Supportive Care
HEVEANA face skin test

Sponsors

Beauty Bright (Thailand) Company Limited
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Healthy female aged between 30-65 year old 2. All skin types 3. Having Fitzpatrick skin type III-V 4. Having clear visible wrinkle at eye corner 5. No wound, scar or any dermatological disorder on face 6. No allergic history of ingredient in any commercially available whitening or anti-wrinkle products in the market 7. Be able to read, communicate and write Thai language 8. Willing to participate in the study after be informed objective, methodology, possible risk and result, and be able to follow the study protocol

Exclusion criteria

Exclusion criteria: 1. Having history of eczema or psoriasis within 6 months before enrolling the study 2. Having history of using steroid, antibiotic, non-steridal andti-inflammatory or antihistamine within 3 days befor enroll the study 3. Having history of using topical medicine on face within 3 weeks before enroll the study 4.Having underlying disease and continuous taking medicine 5. Having history of major operation within 1 year 6. Having history of skin cancer within 1 year 7. Having pregnancy or lactation 8. Heavy smoker or regular drinking or addiction to any narcotic substances 9. Having history of using lightening or anti-wrinkle product within 25 days before enroll the study

Design outcomes

Primary

MeasureTime frame
Skin lightening week 0, 2, 4, 6, 8 Chromameter,Skin melanin and erythrma indexes week 0, 2, 4, 6, 8 Mexameter,Skin roughness and wrinkles week 0, 2, 4, 6, 8 PRIMOS lite

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactNeti Waranuch

Faculty of Pharmaceutical Science

cosnat@nu.ac.th+6655968801

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026