Healthy Thai female subjects
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy female aged between 30-65 year old 2. All skin types 3. Having Fitzpatrick skin type III-V 4. Having clear visible wrinkle at eye corner 5. No wound, scar or any dermatological disorder on face 6. No allergic history of ingredient in any commercially available whitening or anti-wrinkle products in the market 7. Be able to read, communicate and write Thai language 8. Willing to participate in the study after be informed objective, methodology, possible risk and result, and be able to follow the study protocol
Exclusion criteria
Exclusion criteria: 1. Having history of eczema or psoriasis within 6 months before enrolling the study 2. Having history of using steroid, antibiotic, non-steridal andti-inflammatory or antihistamine within 3 days befor enroll the study 3. Having history of using topical medicine on face within 3 weeks before enroll the study 4.Having underlying disease and continuous taking medicine 5. Having history of major operation within 1 year 6. Having history of skin cancer within 1 year 7. Having pregnancy or lactation 8. Heavy smoker or regular drinking or addiction to any narcotic substances 9. Having history of using lightening or anti-wrinkle product within 25 days before enroll the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin lightening week 0, 2, 4, 6, 8 Chromameter,Skin melanin and erythrma indexes week 0, 2, 4, 6, 8 Mexameter,Skin roughness and wrinkles week 0, 2, 4, 6, 8 PRIMOS lite | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Faculty of Pharmaceutical Science