Healthy Thai subjects aged between 30-
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy male and female aged 30-65 years 2.Having normal, dry, oily as well as combination skin 3. Having clear visible wrinkle at eye corner and forehead 4. having experience using a counter brand facial skin care 5. No wound, scar or any skin disease on the face 6. Non-smoking, non-alcoholic and non-drug addiction 7. No history of allergy problem to any commercial available anti-wrinkle problem 8. willing to participate in the project and be able to follow the study protocol 9. willing to give written consent of the volunteer after informing the study detail 10. Be able to abstain from using any anti-wrinkle and moisturizing product rather than the test products during the study period 11. Be able to read, communicate and write Thai language
Exclusion criteria
Exclusion criteria: 1. History of skin eczema, psoriasis within 6 months before enrolling the study 2. History of using steroid, antibiotic, NSAIDs and antihistamine within 3 days before enter the study 3. History of using topical medicine on the face within 3 weeks before enter the study 4. Having chronic diseases and continuous taking medicines 5. History of major operation within 1 year before enter the study 6. History of skin cancer within 1 year before enter the study 7. Pregnancy or lactation 8. Being or having experience in participating other clinical studies within last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin Hydration week 2, 4, 6, 8 Corneometer,Skin Surface Topography Week 2, 4, 6, 8 PRISMOS system,Facial images of the Crow's feet area week 0 and 8 Omnia Imaging system,Self-assessment Questionnair after week 8 Questionnair form | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Faculty of Pharmaceutical Science