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Evaluation of safety and oxidative stress effect of food supplement from Tiliacora triandra (Colebr.) Diels in overweight volunteers

Evaluation of safety and oxidative stress effect of food supplement from Tiliacora triandra (Colebr.) Diels in overweight volunteers

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190517005
Enrollment
Unknown
Registered
2019-05-17
Start date
2019-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy conditions overweight high cholesterol adult

Interventions

starch 2000 mg/day,Tiliacora triandra (Colebr.) Diels capsule 1000 mg/day plus placebo 1000 mg/day,Tiliacora triandra (Colebr.) Diels capsule 2000 mg/day
Placebo,Tiliacora triandra (Colebr.) Diels capsule 1000 mg/day,Tiliacora triandra (Colebr.) Diels capsule 2000 mg/day

Sponsors

Agricultural Research Development Agency (ARDA)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 50 Years

Inclusion criteria

Inclusion criteria: - Live in Khon Kaen, Thailand - Aged between 25-50 years old - Body mass index more than 23 - Cholesterol more than 220 mg/dL -All volunteers should not use other nutraceutical compounds or herbs or drugs which influenced on the nervous system function and bone at least 3 months before participating in this study - On the day of the study, all volunteers felt well and refrain from drinking tea or coffee, or alcohol

Exclusion criteria

Exclusion criteria: • Cardiovascular disease • Respiratory disease • Neuropsychological disorders • Diabetes • Liver disease • Renal disease • Endocrine dysfunction • Autoimmune disease

Design outcomes

Primary

MeasureTime frame
cholesterol 8 weeks clinical laboratory

Secondary

MeasureTime frame
Malondialdehyde level (MDA), Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase act 8 weeks Elisa methods,clinical chemistry 8 weeks clinical laboratory,Complete blood count 8 weeks clinical laboratory,Homeostasis Model Assessment Insulin Resistance (HOMA) index และ atherosclerosis index (AI) 8 weeks clinical laboratory,total phenolic compound 8 weeks Elisa methods

Countries

Thailand

Contacts

Public ContactWipawee Thukhammee

Khon Kaen University

wipath@kku.ac.th+6643348394

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026