Healthy conditions cognitive memory overweight physical fitness psychological fitness adult
Conditions
Interventions
starch is placebo: comparison of different dosages of mulberry capsule ,mulberry capsule 520 mg/day comparison with placebo,mulberry capsule 2600 mg/day comparison with placebo
Placebo,mulberry capsule 520 mg/day,mulberry capsule 2600 mg/day
Sponsors
Agricultural Research Development Agency (ARDA)
Eligibility
Sex/Gender
Female
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: -Live in Khon Kaen, Thailand -Aged between 45-60 years old - All volunteers should not use other nutraceutical compounds or herbs or drugs which influenced on the nervous system function and bone at least 3 months before participating in this study -On the day of the study, all volunteers felt well and refrain from drinking tea or coffee, or alcohol - Early Menopausal transition stage or Late Menopausal transition stage
Exclusion criteria
Exclusion criteria: • Cardiovascular disease • Respiratory disease • Neuropsychological disorders • Diabetes • Liver disease • Renal disease • Endocrine dysfunction • Autoimmune disease • Hematological disorder • Cancer • Brain inflammation, head injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| N100 and P300 12 weeks Event related evoked potentials (ERPs) | — |
Secondary
| Measure | Time frame |
|---|---|
| Computerized batteries test (CDR) 12 weeks computer,Working memory Bond Ladder analogue scale 12 weeks Questionnaire,Psychological symptom using SCL-90 questionnaire 12 weeks Questionnaire,Strength of lower extremities muscles using 30 second chair stand test 12 weeks equipment,Cardio-pulmonary endurance using 6-minute walk test 12 weeks equipment,The changes of hematological and clinical chemistry parameters 12 weeks laboratory,Malondialdehyde level (MDA), Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase act 12 weeks Elisa methods,Acetylcholinesterase and monoamine oxidase activities in serum 12 weeks Elisa methods,total phenolic compound 12 weeks Elisa methods | — |
Countries
Thailand
Contacts
Public ContactWipawee Thukhammee
Khon Kaen University
Outcome results
None listed