Reducing Mortality in Metformin Associated Lactic Acidosis with Fast Track Dialysis: A Controlled Interrupted Time Series Quality Improvement Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190514002

Enrollment

150

Registered

2019-05-14

Start date

2015-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult with Metformin induced lactic acidosis Metformin induced lactic acidosis Acute kidney injury Dialysis

Interventions

MALA fast track dialysis protocol was developed aim to rapid dialysis to correct metabolic acidosis including &#45

criteria for suspected MALA &#45

criteria for dialysis and consult nephrologist &#45

standing order at the emergency room &#45

standing order for dialysis,standard care of MALA in Burirum Hospital and in Maharat Nakornratchasima Hospital before implementing the MALA fast track dialysis protocol.

Experimental Other,Active Comparator Other

MALA fast track dialysis protocol,control

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: The patient who diagnose with MALA

Exclusion criteria

Exclusion criteria: Dialysis patient Sepsis patient

Design outcomes

Primary

Measure	Time frame
Mortality 30 day after admission from electronic medical record	—

Secondary

Measure	Time frame
Dialysis Dependence 90 day not required dialysis,Length of hospital stay admission to death or discharge from hospital day,Time to dialysis duration from admission to start dialysis minute	—

Contacts

Public ContactWatanyu Parapiboon

Maharat Nakornratchasima Hospital

watanyupara@gmail.com0815955154

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026