Infantile Hypertrophic Pyloric Stenosis Preoperative optimization Infantile Hypertrophic Pyloric Stenosis Preoperative optimization Bolus therapy Optimization
Conditions
Interventions
Bolus fluid therapy will be administered as bolus of normal saline 20ml/kg over a span of 1 hour in addition to normal daily maintenance fluids. The number of boluses will be decided as under
Patients with abnormal Cl-
33 or >40 mEq/L will require 2,
3 boluses,
respectively. Patient with normal Cl-
and HCO3 but abnormal K+ <3.5 mmol/lit will be given a single bolus. Each bolus will be given for one hour apart and after the required boluses given then ABG`s and S/E will be performed one hour afte
200ml/kg/day of 5% dextrose in 0.45% saline with the addition of potassium dependent on the patient'
s potassium level until adequate resuscitation will be achieved. ABGS and S/E will be accessed every 8 hourly.
Active Comparator Other,Active Comparator Other
Bolus fluid therapy,Conventional fluid therapy
Sponsors
none
Eligibility
Sex/Gender
All
Age
2 Weeks to 8 Weeks
Inclusion criteria
Inclusion criteria: 1. Infants admitted in the pediatric surgery department with a diagnosis of infantile hypertrophic pyloric stenosis 2. The parents/legal guardian gives consent for inclusion in the study
Exclusion criteria
Exclusion criteria: 1. Patient in renal failure 2. Patient in sepsis 3. Withdraws consent for inclusion in the study 4. A different diagnosis at surgery 5. Plan of surgery changed pre-operatively or intra-operatively 6. Other co-morbidity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to preoperative optimization After start of either conventional or bolus fluid therapy hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital Stay at the time of discharge hours | — |
Countries
Pakistan
Contacts
Public ContactMuhammad Salman Saleem
Department of Pediatric Surgery, The Children's Hospital and the Institute of Child Health, Lahore
Outcome results
None listed