Effects of Vitamin D on Sperm Motility and Antioxidant Capacity in Infertile Male

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190511001

Enrollment

Registered

2019-05-11

Start date

2019-05-11

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D Sperm motility Total motile sperm count Reactive oxygen species Vitamin D Sperm motility Total motile sperm count Reactive oxygen species

Interventions

Add vitamin D 01 nM in DMSO in post&#45

preparation sperm,Add DMSO 0.1 nM in post&#45

preparation sperm

Experimental Drug,Placebo Comparator Drug

Vitamin D,DMSO

Eligibility

Sex/Gender

Male

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: - Abstinent time 2-7 days - Total motile sperm count at least 39M from manual semen analysis - Normal volume from ejaculation (at least 1.5 ml) - Concentration 2 - 60 M/ml - Informed and consent

Exclusion criteria

Exclusion criteria: - Unable to ejaculation by himself - History of varicocele, testicular surgeries including vasectomy - BMI more than 30 kg/m2 - Alcohol drink at least 3 times/week for 1 year - Smoking at least 10 pack year or cessation less than 1 year - Underlying medical conditions; DM type2, chromosomal abnormality - History of cancer or previous chemotherapy/radiation

Design outcomes

Primary

Measure	Time frame
Total motile sperm count 30 minutes Semen analysis	—

Secondary

Measure	Time frame
ROS level 6 hours Immunofluorrescent	—

Countries

Thailand

Contacts

Public ContactPruttaporn Manaeerat

Ramathibodi Hospital

m.pruttapm@gmail.com66991565359

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026