Ocular microbiome in chronic SJS/TEN patients and healthy subjects Ocular microbiome Ocular microbiota Microbial flora Stevens-
Conditions
Interventions
The patients who were in the chronic stage of the disease (more than 1 month after onset of SJS/TEN),Subjects without chronic ocular allergy,
inflammation or any other ocular surface diseases
Other,Other
chronic SJS/TEN patients,healthy subjects
Sponsors
Ratchadapisek Sompotch Research Fund
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: SJS/TEN group Chronic SJS/TEN patients who are able to come for check-up at the out-patient department of King Chulalongkorn Memorial Hospital Healthy group Subjects without chronic ocular allergy, inflammation or any other ocular surface diseases
Exclusion criteria
Exclusion criteria: Participants with these conditions who: o received topical antibiotics within the past 4 weeks. o had acute ocular or periocular infection within the past 4 weeks. o underwent ocular or periocular surgery within the past 3 months. o are using contact lens, or had punctal plug performed previously.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular microbiome of chronic SJS/TEN patients and heathly subjects 3 months Next-Generation Sequencing analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| microbial detection from conventional culture methods in SJS/TEN patients and healthy subjects 3 months conventional culture methods | — |
Contacts
Public ContactThanachaporn Kittipibul
-
Outcome results
None listed