efficacy of omeprazole for prevention of esophageal stricture in grade 2b and 3a corrosive esophageal injuries

A prospective randomized controlled trial on the efficacy of omeprazole for prevention of esophageal stricture in grade 2b and 3a corrosive esophageal injuries

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190504001

Enrollment

Registered

2019-05-04

Start date

2018-04-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal stricture omeprazole corrosive esophagitis esophageal stricture

Interventions

patient with grade 2b and 3a did not treat with omeprazole,patient with grade 2b and 3a treat with omeprazole 80 mg per day for 4 week

No Intervention No treatment,Experimental Drug

without omeprazole,with omeprazole

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: patient with grade 2b and 3a corrosive esophagitis

Exclusion criteria

Exclusion criteria: 1. previous gastric surgery 2. previous esophageal surgery 3. GERD 4. corrosive esophageal perforation

Design outcomes

Primary

Measure	Time frame
esophageal stricture 4 week barium study	—

Secondary

Measure	Time frame
prediction of complication 4 week barium study	—

Countries

Thailand

Contacts

Public ContactPrasit Mahawongkajit

Thammasat University

prasit_md@yahoo.com6681 7339626

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026