The Effect of High Flow Nasal Oxygen Cannula Versus Conventional Oxygen Therapy in COPD Patients with Indication for Long-term Oxygen Therapy: A Pilot Randomized Crossover Study

The effect of high flow nasal oxygen cannula vs conventional oxygen therapy in COPD patients with indication for long term oxygen therapy: a randomized crossover study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190502002

Enrollment

Registered

2019-05-02

Start date

2019-06-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

The HFNC device (Airvo&#45

2ïƒ¤

Fisher & Paykel Healthcare&#44

Auckland&#44

New Zealand),Standard oxygen concentrator

Experimental Device,Active Comparator Device

High&#45

flow nasal oxygen cannula,Conventional low&#45

flow oxygen cannula

Eligibility

Sex/Gender

All

Age

40 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age >/= 40 years 2. Patients with COPD who have an indication for long-term oxygen therapy

Exclusion criteria

Exclusion criteria: 1. Previous history of thoracic surgery 2. Recent exacerbation of COPD within 3 months 3. Recent acute coronary syndrome or acute heart failure within 3 months 4. Patients who have a contraindication for spirometry

Design outcomes

Primary

Measure	Time frame
Respiration 2 weeks Respiratory rate	—

Secondary

Measure	Time frame
Oxygen saturation 2 weeks Pulse oximetry,Transcutaneous CO2 pressure 2 weeks Transcutaneous CO2 pressure monitor,Quality of life 2 weeks St.George Respiratory Questionnaires (SGRQ),Lung function test 2 weeks Spirometry	—

Countries

Thailand

Contacts

Public ContactDr. Nuttapol Rittayamai

Faculty of Medicine Siriraj Hospital, Mahidol University

nuttapol.rit@mahidol.ac.th024197757

Outcome results