The effect of copra manno-oligosaccharides on fecal microbiota of healthy adults

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190426003

Enrollment

Registered

2019-04-26

Start date

2019-04-29

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lacking of Microbiome Microbiome

Interventions

Maltodextrin once daily for 21 days,3gm of copra meal hydrolysate once daily for 21 days ,5gm of copra meal hydrolysate once daily for 21 days

Placebo Comparator Dietary Supplement,Active Comparator Dietary Supplement,Active Comparator Dietary Supplement

Placebo,3gm of copra meal hydrolysate ,5gm of copra meal hydrolysate

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Healthy Volunteers 2. Age 18 - 45 years old 3. BMI 18.5 - 25 4. No antibiotics 3 months before enrollment 5. No probiotics, prebiotics and synbiotics 1 month before enrollment 6. No history of coconut allergic, coconut milk and soy bean

Exclusion criteria

Exclusion criteria: 1. Have Allergic Diagnosis from coconut, coconut milk and soy bean

Design outcomes

Primary

Measure	Time frame
Mircrobiome in Stool Day 0, Day 21, Day 35 16S rRNA gene sequencing, high-performance liquid chromatography ,Clinical score for bowel habit change Day 0, Day 21, Day 35 Stool record chart daily and dietary record 3 times per week (2 weekdays and 1 day on the weekend),Immunoglobulin A Day 0, Day 21 Bio-Plex Pro Human Isotyping kit	—

Secondary

Measure	Time frame
N/A N/A N/A	—

Countries

Thailand

Contacts

Public ContactNarissara Suratannon

Faculty of Medicine Chulalongkorn University

mayzped@gmail.com66812950190

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026