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Pulsed-dye laser as an adjuvant intervention to comedones treatment: A randomized controlled trial

Pulsed-dye laser as an adjuvant intervention to comedones treatment: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190426001
Enrollment
35
Registered
2019-04-26
Start date
2019-10-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erythema index caused by comedone extraction after pulsed-dye laser treatment pulsed-dye laser, comedone extraction, erythema, acne

Interventions

On the PDL-treated side, 595-nm PDL (10-ms pulse duration, 7-mm spot size and 8-J/cm2 fluence) was delivered to the entire side with an additional shot on the extracted sites,PDL sham
PDL,Sham

Sponsors

Ratchadapiseksompotch Fund
Lead Sponsor
No study secondary sponsor
Collaborator

Eligibility

Sex/Gender
All
Age
12 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1.healthy acne participants 2.aged between 12 and 25 years 3.mild to moderate acne severity according to the CASS (grade 2 and 3) 2.able to complete the study.

Exclusion criteria

Exclusion criteria: 1.recent facial laser or light therapy within 3 months 2.use of systemic retinoids within 6 months 3.signs of androgen excess 4.current medication intakes The washout periods to avoid external confounding effects were 2 weeks (topical acne treatments), 4 weeks (oral antibiotics), and 12 weeks (contraceptive medication).

Design outcomes

Primary

MeasureTime frame
Erythema due to comedone extraction 2 and 4 weeks after PDL Erythema index measured by mexameter

Secondary

MeasureTime frame
acne severity (CASS), acne lesion counts and patients' satisfaction 2 and 4 weeks after PDL comprehensive acne severity scale, acne lesion counts and numeric rating scale, respectively

Countries

Thailand

Contacts

Public ContactSusheera Chatproedprai

Division of Pediatric Dermatology, Department of Pediatrics, Faculty of Medicine, CU

susheera.c@chula.ac.th0877727052

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026