Healthy participants Early stage knee osteoarthritis early knee osteoarthritis lymphatic drainage autonomic nervous system physical function
Conditions
Interventions
After collecting baseline data (pre-
test),
participants will be asked to supine on treatment table. For the experimental group,
lymphatic drainage therapy technique will be applied from cervical,
abdominal and leg 45 minutes and measure same as baseline data after treatment (post-
test),Participants in control group will be asked to rest 45 minutes after baseline data collecting (pre-
test) and post-
test will be measured after intervention.
Experimental Other,Experimental Other
Lymphatic drainage therapy,Rest
Sponsors
N/A,N/A
Eligibility
Sex/Gender
All
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: Study I 1. Male or female age between 40-65 years 2. Recreationally active Study II 1. Male or female age between 40-65 years 2. Diagnosed as knee osteoarthritis stage I or II, graded by using American College of Rheumatology (ACR) clinical classification
Exclusion criteria
Exclusion criteria: Study I 1. Renal dysfunction 2. Competitive athlete 3. Active cancer or malignant tumor 4. Body mass index (BMI) more than 24 kg/m2 5. Having cardiovascular or peripheral vascular disorder such as acute angina, heart attack and congestive heart failure which may not control cardiac load increasing 6. Having musculoskeletal disorder such as knee osteoarthritis which can affect lymph flow 7. Pain or any operation at the area which affects lymph flow such as abdominal operation and total knee arthroplasty 8. Having musculoskeletal, neurological, or cardiovascular problem that interferes with the study Study II 1. Renal insufficiency 2. Rheumatoid arthritis (RA) 3. Abnormal skin sensation 4. Skin lesion on the knee joints 5. Active cancer or malignant tumor 6. Body mass index (BMI) more than 24 kg/m2 7. Having cardiovascular or peripheral vascular disorder such as acute angina, heart attack and congestive heart failure which may not control cardiac load increasing 8. Using anti-inflammation medication or intra-articular injection within the last 6 months 9. Pain or any operation at the area which affects lymph flow such as abdominal operation 10. Having musculoskeletal, neurological, or cardiovascular problem that interferes with study such as leg length discrepancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate variability (HRV) Pre and post intervention Polar H7 and Elite HRV smartphone application ,Salivary alpha amylase (sAA) Pre and post intervention Portable salivary amylase monitor, Range of motion (ROM) Pre and post intervention Straight raise leg (SLR) ,Hoffmann reflex (H-reflex) Pre and post intervention Electrical stimulator and surface electromyography ,Pain scale Pre and post intervention Visual Analog Scale (VAS) ,Pressure pain threshold test (PPT) Pre and post intervention Pressure pain threshold algometry,Displacement pain tissue (DPS) Pre and post intervention An algometer probe and synchronizing the end pressure with the light signal,Circumference Pre and post intervention Tape measure , Function activities Pre and post intervention Thai Knee Injury and Osteoarthritis Outcome Score (KOOS) ,Physical functional Pre and post intervention Six-minute walk test | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactAgsipa Honguten
Faculty of Physical Therapy, Mahidol University
Outcome results
None listed