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The effect of the low-dose spironolactone in post adolescent acne: a randomized, double-blind, placebo-controlled trial.

The effect of the low-dose spironolactone in post adolescent acne: a randomized, double-blind, placebo-controlled trial.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190417004
Enrollment
Unknown
Registered
2019-04-17
Start date
2019-02-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acne vulgaris in women who age from 25&#45

Interventions

identical powder tablets,identical active intervention,identical active intervention
placebo,spironolactone 25 mg/day,spironolactone 50 mg/day

Sponsors

Faculty of Medicine, Chulalongkorn University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 45 Years

Inclusion criteria

Inclusion criteria: healty female with moderate degree acne age from 25-45 years old no underlying hepatic or renal dysfuncions no current topical or systemic medications which can aggrating or suppressing acne condition

Exclusion criteria

Exclusion criteria: patients who are preganacy or lactating. patients who are suspected of polycystic ovarian diseases or other abnormalities predisposing to acne conditions. patients with abnormal skin conditions on their face

Design outcomes

Primary

MeasureTime frame
ration of participants who acheive acne severity score of 0 (clear) or almost clear(1) 3 months acne severity score,rate of adversed event reported 3 months number of events

Secondary

MeasureTime frame
the change of total acne count from baseline 3 months the count of acne

Countries

Thailand

Contacts

Public Contactchanat kumtornrut

chulalongkorn university

chanat_1@yahoo.com0814594965

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026