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A Randomized controlled trial comparing effect of Tranexamic Acid use in combined peri-articular and intra-articular injection versus intravenous and intra-articular injection in total knee arthroplasty patient

A Randomized controlled trial comparing effect of Tranexamic Acid use in combined peri-articular and intra-articular injection versus intravenous and intra-articular injection in total knee arthroplasty patient

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190404003
Enrollment
Unknown
Registered
2019-04-04
Start date
2019-02-18
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood loss after total knee arthroplasty Anemia after total knee arthroplasty Swelling after total knee arthroplasty Range of Motion after total knee arthroplasty Bleeding Blood loss Anemia Swelling Range of Motion Tranexamic acids Totalk knee arthroplasty TKA Peri&#45

Interventions

Tranexamic acid route Intravenous plus Intra&#45
articular,Tranexamic acid route Peri&#45
articular plus Intra&#45
articular
Active Comparator Procedure/Surgery,Experimental Procedure/Surgery
IV + IA,PA + IA

Sponsors

Faculty of Medicine Thammasat university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: Unilateral total knee arthroplasty patient

Exclusion criteria

Exclusion criteria: History of tranexamic acid allergy History of Venous Thromboembolism Event (VTE) Bilateral Total knee Arthroplasty patient Patient denied to recruited Patient can not decided by him/herself

Design outcomes

Primary

MeasureTime frame
Calculated blood loss 48-hour post surgery mL—

Secondary

MeasureTime frame
Thigh and leg circumference 48-hour post surgery cm—

Countries

Thailand

Contacts

Public ContactPiya Pinsornsak

Faculty of Medicine Thammasat University

pinpiya2003@yahoo.com0846392078

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026