30 primary breast cancer patient receiving anthracycline chemotherapy breast cancer, anthracycline, cardiotoxicity, exercise
Conditions
Interventions
24 sessions of exercise intervention combined aerobic and resistance exercise during chemotherapy.,routine cancer care including nutrition advices,
self-
Experimental Behavioral,Active Comparator Behavioral
exercise intervention,usual cancer care
Sponsors
6F, No.35, Siao-Dong Road, Tainan, 704, Taiwan, R.O.C
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1)30-65 years old diagnosed with primary breast cancer, (2)breast cancer stage I-III without receiving radiotherapy and target therapy, (3)scheduled for chemotherapy with anthracycline (e.g.doxorubicin, epirubicin), (4)able to follow exercise protocol
Exclusion criteria
Exclusion criteria: (1) acute infectious disease, (2) severe neurological, respiratory and renal deficiencies, (3) severe cardiac or cardiovascular disease (e.g. LVEF<50%), (4) other concurrent malignant disease, (5) life expectancy<6 months, (6) enrolled in studies involving exercise training, (7) unable to walk or stand, (8) ongoing pharmacological cardio-protection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cardiac function of left ventricle ejection fraction before, 3 months and 6 months after chemotherapy echocardiography | — |
Secondary
| Measure | Time frame |
|---|---|
| exercise capacity of maximal oxygen uptake before, 1.5 months, 3 months and 6 months after chemotherapy cardiopulmonary exercise test | — |
Countries
Taiwan
Contacts
Public ContactKunLing Tsai
National Cheng Kung University
Outcome results
None listed