The correlation of area under the curve with single time point concentration of mycophenolic acid and its metabolite in Thai kidney transplant recipients receiving enteric-coated mycophenolate sodium

Status

Active, not recruiting

Phases

Phase 2

Study type

Observational

Source

TCTR

Registry ID

TCTR20190326003

Enrollment

Unknown

Registered

2019-03-26

Start date

2018-08-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thai kidney transplant recipients Enteric&#45

Interventions

Thai kidney transplant patients Who had received EC&#45

MPS&#44

tacrolimus and prednisolone

Health Services Research

Thai kidney transplant receiving enteric&#45

coated mycophenolate sodium

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Aged 18 years or older. Kidney transplant Who had received EC-MPS + tacrolimus + prednisolone

Exclusion criteria

Exclusion criteria: Patients with multiple organ transplantation Patients who are taking concomitant drug that might have drug interaction such as antacid, antibiotic and high protein binding drug.

Design outcomes

Primary

Measure	Time frame
single time point concentration of MPA and its metabolite 0, 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 6, 8, 10 and 12 hr plasma/ measure by LC-MS/MS	—

Secondary

Measure	Time frame
cut-off point concentration of MPA for indicating MPA exposure more than 30 Âµgâ€¢h/l - ROC curve	—

Countries

Thailand

Contacts

Public ContactNapatsanan Tanathitiphuwarat

Faculty of Pharmacology, Chulalongkorn University

yok8936@hotmail.com6696-760-4997

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

The correlation of area under the curve with single time point concentration of mycophenolic acid and its metabolite in Thai kidney transplant recipients receiving enteric&#45;coated mycophenolate sodium