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Comparison of efficacy of oral and vaginal progesterone to prevent preterm birth in pregnant women with short cervix: Randomized controlled trial

Comparison of efficacy of oral and vaginal progesterone to prevent preterm birth in pregnant women with short cervix: Randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190324001
Enrollment
Unknown
Registered
2019-03-24
Start date
2017-07-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm delivery Preterm delivery cervical length progesterone

Interventions

Micronized progesterone 200 mg orally before bedtime,Micronized progesterone 200 mg vaginal suppository before bedtime
Experimental Drug,Active Comparator Drug
oral progesterone,vaginal progesterone

Sponsors

none
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
10 Years to No maximum

Inclusion criteria

Inclusion criteria: All pregnancy with 20-25 weeks of gestation women who visited ANC clinic at SPS Hospital A singleton Cervical length 25 mm or less by transvaginal ultrasound measure

Exclusion criteria

Exclusion criteria: History of allergy of progesterone Fetal anomaly Fetal aneuploidy Cervical incompetence

Design outcomes

Primary

MeasureTime frame
preterm birth before 34 weeks until the patients delivery medical record of labor at Suspasittiprasong Hospital,preterm birth before 37 weeks until the patients delivery medical record of labor at Suspasittiprasong Hospital

Secondary

MeasureTime frame
maternal obstatic complication After discharge from Suspasittiprasong Hospital due to delivery medical record at Suspasittiprasong Hospital,neonatal complication After discharge from Suspasittiprasong Hospital due to delivery medical record at Suspasittiprasong Hospital,change in cervical length after progesterone was used 4 weeks after the first measure at date of enrollment measure by transvaginal ultrasound

Contacts

Public ContactParinya Chamnan

Department of Obstetrics and Gynecology, Sappasitthiprasong Hospital

princdos04@gmail.com04524497

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026