A randomized, controlled trial, double blinded comparing the effectiveness of post-operative pain control between adductor canal block and local injection for arthroscopic assisted anterior cruciate ligament reconstruction with semitendinosus graft

A randomized, controlled trial, comparing the effectiveness of post-operative pain control between adductor canal block and local analgesia for semitendinosus graft, anterior cruciate ligament reconstruction

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190320003

Enrollment

Registered

2019-03-20

Start date

2019-07-08

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative pain control after arthroscopic assisted anterior cruciate ligament reconstruction with semitendinosus graft Anterior cruciate ligament reconstruction Post-operative pain control Morphine consumption Adductor canal block Local analgesia

Interventions

Post operative pain control of artroscopic assisted anterior cruciate ligament reconstruction with semi&#45

tendinosus graft with ultrasound guide adductor canal block by 2 anestiologists with 0.25% isobaricity bupivacaine 20 ml. ,Post operative pain control of artroscopic assisted anterior cruciate ligamen

tendinosus graft by Local injection cocktail (Intra and periarticular knee injection with Morphine 3 mg&#44

transamine 1 gm and ketorolac 30 mg).

Experimental Drug,Experimental Drug

Adductor canal block,Local injection

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patient at 18 years or more Patient who undergo primary arthroscopic assisted anterior cruciate ligament reconstruction with semitendinosus graft

Exclusion criteria

Exclusion criteria: Contraindication for spinal anesthesia Renal insufficient (GFR<30ml/min) High risk for cardiovascular event and cerebrovascular event Underlying : Pepticulcer, GI bleeding Ipsitlateral previous knee surgery Concomittant knee ligament injury or fracture Contraindication for adductor canal block Drug allergy Alcohol or Drug intoxication Cannot operate due to abnormal mental status

Design outcomes

Primary

Measure	Time frame
Total morphine consumption Post operation at 48 hr ml./recorded by intravenous patient control analgesia	—

Secondary

Measure	Time frame
Post operative pain score Post operation at PACU, 6, 12, 24, 48 hr numerical rating scale,Patient satisfaction Post operation at 48 hr numerical rating scale,Performed Straight leg raising test Post operation at 24 hr Can or cannot performed,Complication any time Data record,Range of motion of knee Post operation at 24, 48 hr degree,Motor power of quadriceps muscle Post operation at 24 hr MRC scale,Morphine consumption Post operation at PACU, 6, 12, 24, 48 hr ml./recorded by intravenous patient control analgesia	—

Measure

Time frame

Post operative pain score Post operation at PACU, 6, 12, 24, 48 hr numerical rating scale,Patient satisfaction Post operation at 48 hr numerical rating scale,Performed Straight leg raising test Post operation at 24 hr Can or cannot performed,Complication any time Data record,Range of motion of knee Post operation at 24, 48 hr degree,Motor power of quadriceps muscle Post operation at 24 hr MRC scale,Morphine consumption Post operation at PACU, 6, 12, 24, 48 hr ml./recorded by intravenous patient control analgesia

—

Countries

Thailand

Contacts

Public ContactKhananut Jaruwanneechai

Faculty of Medicine, Khon Kaen University

j.khananut@gmail.com0941945694

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026