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The effectiveness of ya-thor-ra-nee-san-tha-kat compare with naproxen tablets for the treatment in chronic Myofascial pain syndrome

The effectiveness of ya-thor-ra-nee-san-tha-kat compare with naproxen tablets for the treatment in chronic Myofascial pain syndrome

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190318002
Enrollment
Unknown
Registered
2019-03-18
Start date
2018-03-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

This study included patients with myofascial pain syndrome&#44

Interventions

Conventional treatment of myofascial pain syndrome,Thor&#45
ra&#45
nee&#45
san&#45
tha&#45
kat is the name of Thai traditional medicine consisted of black peper and aloe as major ingredients. This medicine is used to relieve muscle pain.
Active Comparator Drug,Experimental Drug
250 mg naproxen tablets twice a day after meals ,500 mg capsules of Thor&#45
kat once daily before bed

Sponsors

Khon Kaen University
Lead Sponsor
Faculty of Pharmaceutical Sciences
Collaborator

Eligibility

Sex/Gender
All
Age
25 Years to 75 Years

Inclusion criteria

Inclusion criteria: adults aged between 25-75 years who had been diagnosed with myofascial pain syndrome affecting both trapezius muscles (at least one active trigger point). Chronic pain (not less than 3 months) in the neck or shoulder area Pain score not less than 6 out of 10. Not undergone other treatments including massage, acupuncture Not undergone the operation in the muscle area within 1 year prior to this study No allergy history with NSAIDS or herbal drugs

Exclusion criteria

Exclusion criteria: Pregnancy Patients with infectious diseases, tuberculosis, diabetes, cancer hypertension, kidney diseases, liver diseases, epilepsy handicapped person paralysis patients who have muscle pain from other causes including radiculopathy, myelopathy, disc herniation, osteoarthritis

Design outcomes

Primary

MeasureTime frame
Numerical pain score 14 days Numeric Pain Rating Scale ,Angle of joint rotation 14 days Cervical range of motion,The minimum pain pressure threshold 14 days Goniometer

Secondary

MeasureTime frame
Ceatinine clearance 14 days Clinical blood test,Aspartate Aminotransferase 14 days Clinical blood test,Alanine Aminotransferase 14 days Clinical blood test

Countries

Thailand

Contacts

Public ContactTANIT PADUMANONDA

Khon Kaen University

tanpad@kku.ac.th094-5309120

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026