Comparative study on the impact of combined oral contraceptive pills and Progestrogen only pills on the prevalence of bacterial vaginosis using Nugent score : a randomized-controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190313002

Enrollment

200

Registered

2019-03-13

Start date

2019-03-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To study prevalence of bacterial vaginosis

Interventions

Combine oral contraceptive pills [EE 30 /desogestrel 150],Desogestrel 75microgram

Experimental Drug,Experimental Drug

Marvelon,Cerazette

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Reproductive age 18-45 years old 2. Women who need oral contraception for 3 months 3. Healthy and no current medication 4. Regular menstrual cycle for 3 consecutive months 5. No history of abnormal vaginal discharge or clinical of vaginitis in 1 month 6. History of postpartum for at least 6weeks and no breastfeeding

Exclusion criteria

Exclusion criteria: 1. History of abnormal uterine bleeding 2. Severe underlying disease 3. History of hormonal contraceptive use within 1 month before enroll in the study 4. Allergic History or contraindication of hormonal contraceptive pill 5. History of prolong antibiotic use or immunosuppressive drug usen 5. Thai women Pregnant women

Design outcomes

Primary

Measure	Time frame
To compare prevalence of bacterial vaginitis on the impact of coc and pop 84 days Nugent score	—

Secondary

Measure	Time frame
To compare the prevalence of STD infection on the impact of COC and POP 84 days Wet smear	—

Countries

Thailand

Contacts

Public ContactManopchaii Thamkhantho

Faculty of Medicine Siriraj Hospital

Tmanopchai@hotmail.com+66819323378

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Comparative study on the impact of combined oral contraceptive pills and Progestrogen only pills on the prevalence of bacterial vaginosis using Nugent score : a randomized&#45;controlled trial